Analgesia o ka Snake Venom Pada maloʻo paʻa kiʻi

Analgesia o ka Snake Venom Pada maloo maloo

ʻO ka wehewehe pōkole:

ʻO ka hoʻohana ʻana o ka nahesa ʻawaʻawa i loko o agkistrodon (ʻelima-step snake): analgesia
Loaʻa i ka snake venom nā hana o ka hoʻokuʻu ʻana i ka makani a me ka dehumidification, anticoagulation a me antithrombus, wehe i ka fibrinogen, hōʻemi i ka viscosity koko, hoʻonui i nā kīʻaha koko, hoʻomaikaʻi i ka microcirculation a hoʻohaʻahaʻa i nā lipids koko.ʻO ka mea ʻawaʻawa o ka agkistrodon agkistrodon he lāʻau lapaʻau kiʻekiʻe, aia nā ʻāpana pharmacological o ka hoʻoikaika ʻana i ka coagulation, fibrinolysis, anti-cancer a me analgesia.ʻO nā hana nui:
1. Analgesia.
2. Hoʻohaʻahaʻa i ke koko.
3. Hemostasis a me ka anticoagulation.
4. ka hopena anti-cancer.
5. ka mālama ʻana i ka thrombosis cerebral a me ka vasculitis.
6. E mālama i ka maʻi ʻōpū a me ka duodenal.
7. ʻo ia ka serum anti-koko.
8. ʻO ka pūʻali koa a me ka lāʻau lapaʻau

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Analgesia

I nā makahiki i hala iho nei, ʻo ka noiʻi mai ka ʻāina ma ka hema o Anhui lōʻihi noded lua viper, ka viper a me ka cobra hoʻomaʻemaʻe o ka lāʻau lapaʻau kūpaʻa kiʻekiʻe coagulation mokuʻāina enzyme, protein C ho'ā (PCA) a me nā mea bioactive like ʻole, ua hōʻoia nā haʻawina hoʻokolohua. hiki i ka mea hana ke hoʻopili i ke kaʻina coagulation, hoʻopili i ka platelet adhesion, aggregation a me ka pale ʻana i ka hana vascular endothelial cell function, me ka hana kiʻekiʻe, anticoagulation, thrombolysis hopena, He mea nui ia no ka pale ʻana a me ka mālama ʻana i nā maʻi thrombotic clinical a me ka hoʻomaikaʻi ʻana i ke koko hypercoagulability. .Ua ʻike pū ʻia ua hiki i ka SNAKE venom PCA ke pepehi pono i nā maʻi leukemia K562 a keʻakeʻa i ka metastasis o nā maʻi maʻi maʻi, a he ākea loa kāna noi noiʻi.Laboratory pono e hana a hoʻopau i ka 'āina maoli 'epekema waihona a me ka 'oihana o ke ola kino a me ka 'epekema noiʻi kālā i anhui keʻena olakino, 'oihana o ka hoʻonaʻauao "kuhikuhi e honi i ka viper mea make kumu DIC mechanical", "kuhikuhi e honi i ka viper i na holoholona kumu. noiʻi hoʻokahe koko", "enzyme standard method of snake injury diagnosis and differential diagnostic of its snake family" a pēlā aku kekahi mau kumuhana noiʻi;Aia nā papahana o kēia manawa: "E aʻo i ka nele o ka hemorrhagic anticoagulant protein i Pentaphylla pentaphylla", "E aʻo i ka molecular mechanism of the effect of PCA on vascular endothelial function of Ankistrodon agkistrodon venom", "Study on the molecular biology of PCA antitumor cells in Snake venom", a me ka hoʻokaʻawale ʻana a me ka hoʻomaʻemaʻe ʻana i nā ʻāpana neuroanalgesic i loko o Cobra venom.

I ka makahiki 1976, ua hoʻomohala maikaʻi ʻo Kunming Institute of Zoology, ʻāina ʻo Yunnan i ka "Ketongling" mai ka snake venom no ka mālama ʻana i nā maʻi ʻeha like ʻole, a loaʻa ka hopena analgesic kūʻokoʻa.Ua hoʻomohala ʻo Cao Yisheng i ka "Compound Ketongning" i ka mālama ʻana i ka ʻeha neuropathic, ka ʻeha maʻi kanesa a me ka hoʻohui lāʻau i hōʻike i kahi hopena maikaʻi loa.Ma muli o kāna hana analgesic kiʻekiʻe a me ka hoʻohui ʻole ʻana, hoʻohana ʻia nā analgesics snake venom e pani ai i ka morphine i ka mālama ʻana i ka ʻeha maʻi maʻi hope loa.