Hoʻohana ʻia ʻo Snake Venom e hoʻōki i ke koko a me ka anticoagulation

ʻO ka wehewehe pōkole:

I ka makahiki 1981, lawe ʻia ka defibrase a hoʻomohala ʻia e Kunming Institute of Zoology, Yunnan, Kina, mai ka ʻawaʻawa o ka nahesa pentameter Kina i hala i ka loiloi loea a ua hoʻohana ʻia i ka mālama ʻana i nā hihia 333 o ka thrombosis vascular, me 242 mau hihia o ka thrombosis cerebral, me ka helu kūpono o 86.4%.Ua hoʻohana ʻia ka agkistrodon agkistrodon acidase, i hoʻomohala ʻia e China Medical University a me Shenyang Pharmaceutical College, i ka mālama ʻana i nā occlusive vascular me nā hopena lapaʻau maikaʻi.Ua hoʻomohala ʻo Snake venom Laboratory o China Medical University i ka snake venom antacid enzyme, hiki ke hōʻemi i ka lipids koko, hoʻonui i nā kīʻaha koko, hoʻemi i ka ʻike o ka thrombin i loko o ke koko, hoʻonui i ka prostacyclin, a hoʻomaha i ka ʻiʻo maʻemaʻe o nā kīʻaha koko.ʻO ia kahi hoʻomākaukau anticoagulant thrombolytic kūpono.

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

1. ʻO ka "defibrase" i unuhi ʻia a hoʻomohala ʻia mai ka mea make o nā pentapodes Kina ua ʻae ʻia e Kunming Institute of Zoology, Yunnan, Kina ma 1981. Ua hoʻohana ʻia i ka mālama ʻana i nā hihia 333 o ka thrombosis vascular, me 242 mau hihia o ka thrombosis cerebral, me kahi ka helu kūpono o 86.4%.
2. ʻO Agkistrodon agkistrodon acidase, i hoʻomohala pū ʻia e China Medical University a me Shenyang Pharmaceutical College, ua loaʻa i nā hopena lapaʻau maikaʻi i ka mālama ʻana i nā occlusives vascular.
3. Ua hoʻomohala ʻo Snake venom Laboratory o China Medical University i ka snake venom antacid enzyme, hiki ke hōʻemi i ka lipids koko, hoʻonui i nā kīʻaha koko, hoʻemi i ka ʻike o ka thrombin i loko o ke koko, hoʻonui i ka prostacyclin, a hoʻomaha i ka ʻiʻo maʻemaʻe o nā kīʻaha koko.ʻO ia kahi hoʻomākaukau anticoagulant thrombolytic kūpono.
4. Anti-five-snake snake venom
He ʻano lāʻau lapaʻau ʻo Antivenomous snake serum, ʻo ia ka mea i hana ʻia mai ka plasma lio lio i hoʻopaʻa ʻia me ka agkistrodon (agkistrodon) toxin, i hoʻopaʻa ʻia e ka enzyme a paʻakai ʻia.Loaʻa iā ia he 2000U antivenomous snake serum.Ua hoʻomākaukau ʻia kēia kānana e ka ʻeli ʻana o ka enzyme a me ka paʻakai ʻana mai ka plasma lio i hoʻopaʻa ʻia me ka lāʻau make mai A. agkistrodon.

5. ʻOihana-university-noiʻi hui
Ua hui pū ʻo Mashan Longshe Snake Industry Co., Ltd. me ka snake Venom Institute o Guangxi Medical University e hoʻolako i nā mea ʻawaʻawa kiʻekiʻe kiʻekiʻe no ka manawa lōʻihi, i hoʻohana ʻia no ke aʻo ʻana i ka biochemistry, molecular biology a me ka pharmacology o ka snake venom protein, a ua noho pelekikena ma mua o 10 papahana e like me ka National Natural Science Foundation a me Guangxi Science and Technology Department projects.Ua lanakila ʻo ia i ka makana ʻelua o Guangxi Science and Technology Progress Award a me ke kolu o ka makana o Guangxi Science and Technology Progress Award.

6. He mea hemostatic ka snake hemagglutinin me ka thrombin kinase-like, hiki ke hoʻololi i fibrin ma ka hydrolyzing fibrinogen, no laila e hoʻonui ai i ka hana coagulation o ke kino;Loaʻa i kēia huahana ka hana o ka hoʻomaikaʻi ʻana i ka platelet aggregation, hiki ke hoʻihoʻi ʻole i ka hōʻuluʻulu ʻana o nā platelets, pēlā e hoʻomaikaʻi ai i ka hana coagulation, akā ʻaʻole ia e hāpai i ka platelet aggregation i loko o nā kīʻaha koko paʻa.
Hemocoagulation o agkistrodon agkistrodon ma ke ʻano he mea kōkua no ka hemostasis o ka ʻeha papa ma ke ʻoki ʻana.