Hana anti angiogenic o ka mea K o Agkistrodon acutus venom mai Guangxi

Pahuhopu E aʻo i ka hopena anti-angiogenesis o ka hakina K mai Guangxi Agkitrodon Acutus venom.Nā Hana Ua ana ʻia nā hopena pale o ka hakina K e kūʻē i ka laina endothelial cell ECV304 in vitro e MTT, ʻike ʻia ka hoʻopili ʻana o nā cell ECV304 i ka cell fibronectin (FN) e ka hakina K.Ua loiloi ʻia ka hopena anti-angiogenesis ma vivo e ka chick embryo chorioallantoic membrane (CAM) assay.Nā hualoaʻa Ua kāohi nui ʻia ka hoʻonui ʻana o ka laina kelepona endothelial ECV304 e ka hapa K i ka manawa a me ke ʻano o ka hopena.Ua kāohi pū ʻo Fraction K i ka hoʻopili ʻana o ka endothelial cell i ka FN a me ka hoʻokumu ʻana o ka tubule ma CAM.Manaʻo He hana anti-angiogenesis ka hakina K.%