ʻO ka hoʻouka kaua antitumor a me ka metastasis o Agkistrodon acutus venom component ACTX-8 ma ka ʻaoʻao hema o Anhui.

Pahuhopu E noiʻi i ka hopena a me ka pae o ka mea o Agkistrodon acutus venom ACTX-8 i ka hoʻopili ʻana a me ka hoʻouka ʻana o ka maʻi maʻi maʻi ʻaʻai cervical cell Hela

Pūnaehana pani.Ua uhi ʻia ʻo Fibronectin i loko o ka pā 96-well plate.Ua hele nā ​​pūnaewele Hela i ka 0, 2.5, 5, 10, 20, 40 g/ml o ACTX-8

Ma hope o ka mālama ʻana, ua ʻike ʻia ka pili ʻana me Fibronectin, a ua ʻike ʻia ka helu o nā cell pili e MTY;Ka ʻike ʻana i ka hoʻouka kaua a me ka neʻe ʻana e ke ʻano kelepona ʻo TransweU

Hoʻololi i nā hiki;Ua ʻike ʻia ka paʻa hoʻokūkū ma waena o ACTX-8 a me Fibronectin a me Hela cell membrane e ka flow cytometry.Nā hualoaʻa:

Ma hope o ka mālama ʻana me ACTX-8, ua emi ka hoʻopili ʻana o nā pūnaewele Hela iā Fibronectin, a ua hōʻike ʻia ka hoʻokolohua cell transwell e neʻe ana nā cell Hela.

Hoʻemi ʻia ka hiki o ka neʻe ʻana a me ka hoʻouka ʻana.Hōʻike nā hopena cytometry kahe e hiki i ka ACTX-8 ke hoʻokūkū i ka hoʻopaʻa ʻana i ka mea loaʻa o Fibronectin ma ke kelepona.