Ka holomua o ka noiʻi ʻana o ka snake venom thrombin like enzyme

ʻO ka snake venom thrombin like enzyme (TLE) he protease serine o ka ʻohana trypsin, ʻoi aku ka mālama ʻia o nā kaʻina me trypsin.Loaʻa iā ia ka hana arginine esterase, hiki ke hana pololei i ka fibrinogen, hoʻokaʻawale i ka ʻāpana o ka paʻa peptide Arg2Gly ma kahi kikoʻī o ka mole fibrinogen, hoʻokuʻu i ka fibrinopeptide A (FPA) a i ʻole B (FPB. ʻO ka kānana gel a me ka chromatography affinity Hoʻohana nui ʻia ka chromatography affinity ma muli o kona kiʻekiʻe o ka hoʻokaʻawale ʻana a me ka hoʻihoʻi kiʻekiʻe o ka laʻana. P3 a me P4 mai ka mea make o Agkistrodon acutus ma Fujian ma o ka hoʻohana ʻana i nā kaʻina hoʻomaʻemaʻe like ʻole. Hōʻike nā haʻawina he hana thrombin lāua ʻelua, akā ʻo EDTA ke kāohi ʻana i ka hana thrombin o ka mea P4 a keʻakeʻa loa i ka hana coagulase o ka mea P3. ʻAʻohe o ka Component P4 ka hana o ka activating factor