E aʻo e pili ana i ka hopena pale o nā polypeptides liʻiliʻi liʻiliʻi mai Agkistrodon acutus venom ma nā pūnaewele A2780.

[Abstract] Pahuhopu No ka noiʻi ʻana i ka hopena paʻa o ka hakina polypeptide molekala liʻiliʻi (ʻāpana K) mai Agkistrodon acutus venom i ka hoʻonui ʻana o ke kanaka ovarian cancer cell line A2780 a me kāna hana.Ua ho'ohana 'ia ka MTT assay no ka 'ike 'ana i ka ulu 'ana o ka mea K ma nā laina ma'i 'a'ai;Ua ʻike ʻia ka hopena anti-cell adhesion o ka ʻāpana K e ka hoʻāʻo adhesion;Ua hoʻohana ʻia ʻo AO-EB double fluorescence staining a me flow cytometry e ʻike i ke ʻano o ka apoptosis.Nā hualoaʻa K 'āpana i keakea i ka proliferation o ke kanaka ovarian maʻi 'aʻai maʻi 'aʻai laina A2780 i ka manawa-hopena a me ka dose-hopena pili, a hiki ke pale aku i ka adhesion o nā pūnaewele i FN.Ua ʻike ʻia ka Apoptosis e ka AO-EB pālua fluorescence staining a kahe cytometry.Manaʻo Manaʻo ʻO ka Component K he hopena hoʻoweliweli koʻikoʻi i ka hoʻonui ʻana o ke kanaka ovarian cancer cell line A2780 in vitro, a pili paha kona ʻano me ka adhesion anti-cell a me ka induction o apoptosis.