Pono e mālama ʻia ʻo Snake Venom mai Agkistrodon (ʻelima-step Snake) me kahi kiʻi i hōʻike ʻia me ka Antihematic Serum.

Pono e mālama ʻia ʻo Snake Venom mai Agkistrodon (ʻelima-step Snake) me kahi Serum Antihematic.

ʻO ka wehewehe pōkole:

Ua mālama ʻia ʻelua mau hoʻokolohua lapaʻau, kahi hoʻāʻo i hoʻopaʻa ʻia i ka placebo a me kahi hoʻāʻo maikaʻi.ʻO nā ʻeha a pau e kahe ana i ke koko ma ka ʻoki ʻana i ka paia o ka ʻōpū i ka ʻoki ʻana.ʻO nā kuhikuhina lapaʻau koʻikoʻi ʻo ia ke kahe koko, ka manawa hemostasis a me ke kahe koko ma kēlā me kēia ʻāpana.Hoʻokaʻawale ʻia kahi placebo i nā hoʻokolohua lapaʻau i 180 mau hihia o ke kanaka: ka hapa o nā helu like ʻole i kahi placebo, 2 u a me 3 u ʻekolu mau pūʻulu, ʻo ka preoperative 15-20 mau minuke hoʻokahi intravenous dosing, nā hualoaʻa e hōʻike i kēia mau kumu ʻelua i ke koko, ka manawa koko a ʻoi aku ka maikaʻi o ke kahe o ke koko ma kēlā me kēia ʻāpana wahi ma mua o ka placebo, akā ʻaʻohe pilina pane ʻana ma waena o ʻelua pūʻulu.Ma ka ho'āʻo hoʻomalu maikaʻi, aia nā maʻi 324 i ka hui hoʻokolohua a me nā maʻi 108 i ka pūʻulu hoʻomalu, a ua hāʻawiʻia kahi hoʻokahi o 2U i loko o ka hui hoʻokolohua 15-20 mau minuke ma mua o ke kāpiliʻana ma ka hoʻokahi intravenous injection.ʻAʻohe hopena ʻino i ʻike ʻia ma nā hoʻokolohua ma luna.

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Ua hōʻike ʻia nā haʻawina e hana nui kēia mau nahesa ʻawaʻawa i ke koko a me nā neurotoxins, hiki ke hoʻoulu i ka diffuse intravascular coagulation (DIC) a ma hope o ke kahe ʻana o ke koko, ka haʻalulu a me ka hāʻule ʻole o nā kino.Ma muli o ke aʻo ʻana o ke koko o ka snake venom ma ka ʻaoʻao hema o Anhui, ua ʻike ʻia ʻo DIC kekahi o nā hiʻohiʻona o nā maʻi ʻeha nahesa me ka make mua, he ʻokoʻa ia mai ka ʻōlelo kuʻuna o DIC.No laila, ua manaʻo ʻia ka manaʻo o "DIC like" syndrome i nā maʻi nahu nahesa no ka manawa mua ma Kina (1988).Ua ʻike ʻia ʻo TLE a me FE ke kumu nui o kēia "DIC like" (1992).He mea nui kēia e wehewehe i nā ʻano o ka hoʻololi ʻana o ke koko i nā poʻe maʻi me ka snake snake ʻelima, a hāʻawi pū i kahi kumu kumu no ka hoʻohana ʻana i nā antivenom kūikawā e mālama i kēia pilikia.

Ma ka noiʻi e pili ana i ke kahe koko i hoʻokumu ʻia e ka ʻawaʻawa ʻelima-snake, ua ʻike pū ʻia ka hopena o kēia snake i nā ʻāpana ʻekolu o ka ʻōnaehana hemostatic o ke kino (coagulation factor, platelets a me ka paia o ke koko), ma waena o ke kahe koko. pili pono ka toxin i ka permeability o nā capillaries.I ka manawa like, ua ʻike ʻia ʻaʻole maʻalahi ka hoʻoponopono ʻana i ke koko nui a me ka pehu ʻana o nā lālā ʻeha, e pili ana i ka keakea ʻana o ke kahe koko o ka thoracic duct lymphatic coagulation factor a me ka maikaʻi ʻole o ka holo lymphatic.Ma ka hana lōʻihi me ka qimen Snakebite Institute, ua hana nui kēia mau hopena noiʻi kumu a hoʻohana ʻia i ka hoʻolālā maikaʻi ʻana i ka hoʻolālā lapaʻau no ka snakebite a me ka hōʻoia ʻana i ka palekana o nā maʻi snakebite, a ua hoʻokō i nā hopena koʻikoʻi.Ua lanakila nā mea noiʻi i ka makana ʻepekema a me ka ʻenehana no ka ʻāina ʻo Anhui, ka makana ʻepekema a me ka ʻenehana holomua o ka ʻāina ʻo Anhui (1993), ke Kuhina o ke ola (A) Grade Science a me ka ʻenehana Achievement Group Award (1991);I ka makahiki 1989, ua hui pū ka hui me Wuhan Institute of Biological Products e hoʻomohala i ka antibody monoclonal e kūʻē i ka penta snake venom thrombin, ʻo ia ka lanakila mua ma Kina.Ma 1996, hui pū ka hui a hoʻomohala i nā huahana thrombin me ka Institute of Biological Products and Drugs of Jinan Military Command (Yuwei Drug Approval No. 118004, Patent CN1141951A).